The Truth About Marijuana and Glaucoma
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Glaucoma is a progressive eye condition characterized by damage to the optic nerve, often related to elevated intraocular pressure (IOP). Marijuana, derived from cannabis, has been explored as a potential means to lower that pressure. Researchers have studied cannabinoids for their IOP-lowering properties and possible neuroprotective effects. However, there is still much discussion regarding its efficacy, side effects, and practicality as a long-term treatment.
In many studies, marijuana has been shown to reduce IOP by interacting with the endocannabinoid system (ECS) present in the eye. Despite these promising effects, the reduction lasts only a few hours and may come with significant side effects. Our glaucoma specialists encourage patients to understand the science behind glaucoma treatment and the limitations of marijuana before considering any changes to their treatment plan.
Below, we break down the mechanisms involved, the research findings, and the concerns that arise when considering marijuana as a treatment option for glaucoma. Associated Eye Physicians & Surgeons of NJ proudly offers eye care at four convenient locations: Belleville serving Essex County, Rahway serving Middlesex and Union Counties, Jersey City serving Hudson County, and Union serving Union County.
Dr. Paige Hershkin, a board-certified ophthalmologist, specializes in cataract surgery and glaucoma care.
Glaucoma and Intraocular Pressure Connection
Glaucoma is usually associated with elevated IOP, which results from a buildup of aqueous humor—a clear fluid in the eye produced by the ciliary body. This fluid naturally drains through structures like the trabecular meshwork and Schlemm’s canal. When too much fluid accumulates, the pressure inside the eye increases, damaging the optic nerve and leading to vision loss if untreated.
Lowering IOP is critical in managing glaucoma. Studies such as the Ocular Hypertension Treatment Study (OHTS) and the Early Manifest Glaucoma Trial (EMGT) have shown significant evidence that reducing IOP slows the progression of glaucoma. In these studies, even a 25% reduction in IOP resulted in up to a 50% decrease in the risk of worsening glaucoma. Given this relationship, any treatment able to reduce IOP merits consideration, which is why marijuana’s potential role has generated interest.
Marijuana's Impact on IOP
Studies have consistently shown that marijuana can decrease IOP by approximately 20–30% for a period of 3–4 hours after administration. However, this short duration demands repeated dosing throughout the day to maintain lowered pressure, which introduces significant challenges and concerns.
Cannabinoid Mechanisms in the Eye
Benefits and Limitations: Research Findings
In controlled studies, marijuana has demonstrated a consistent ability to reduce intraocular pressure:
Comparison with Standard Treatments
Standard glaucoma therapies aim to maintain a consistent reduction in IOP across a full 24-hour cycle. These treatments include topical eye drops, laser therapy, and surgical interventions. Here’s how they compare with marijuana-based approaches:
Practical Limitations
and Challenges
Despite the documented IOP-lowering effect, several factors limit marijuana’s viability as a treatment for glaucoma:
Routes of Administration
Your Trusted Eye Doctors Serving Central and Northern NJ
Understanding the potential implications of marijuana use in glaucoma treatment is crucial for effective management of this progressive condition. At Associated Eye Physicians & Surgeons of New Jersey, we emphasize informed decision-making when considering all treatment options. While marijuana shows promise in reducing intraocular pressure, it’s important to weigh its benefits against potential drawbacks. Trust our eye doctors to help you navigate your glaucoma treatment in a way that prioritizes your long-term vision health. Experience personalized, expert eye care by scheduling an appointment with our eye doctors in Belleville, Jersey City, Rahway, or Union, NJ.
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- Glaucoma
- Glaucoma Treatment
- Minimally Invasive Glaucoma Surgeries (MIGS)
- Can my Medication Raise Eye Pressure?
- Glaucoma Symptoms and Stages
- Marijuana and Glaucoma
- Living with Glaucoma
- Selective Laser Trabeculoplasty (SLT)
- Dry Eye in Glaucoma Patients
- What is a Glaucoma Suspect?
- YAG Laser Iridotomy
- iDose TR
At Associated Eye Physicians of NJ, we’ve built our reputation on care that’s local, personal, and easy to get to. With offices in Belleville, Union, Jersey City, and Rahway, we’re proud to serve a wide range of communities across North and Central Jersey. Our Belleville team welcomes patients from all over Essex County, including Newark, Bloomfield, and Nutley. Rahway welcomes patients from across Middlesex and Union Counties, including nearby patients from Elizabeth, Avenel, Woodbridge, and Perth Amboy. Our Union office is a favorite for families from Union County, especially for those in Elizabeth and Cranford. And in Jersey City, we care for Hudson County residents, including our neighbors in Hoboken and Bayonne.