Conjunctival Papilloma: What You Need to Know


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Conjunctival papilloma is a benign growth occurring on the surface of the eye, typically arising from the squamous epithelial cells. It may appear as a pedunculated (stalked) or sessile (flat) lesion and often displays a cauliflower-like or fingerlike appearance. Though non-cancerous, the condition may cause discomfort, cosmetic concerns, and occasional visual disturbances, making it important to understand its causes, presentation, and treatment options. Associated Eye Physicians & Surgeons of NJ proudly offers eye care at four convenient locations: Belleville serving Essex County, Rahway serving Middlesex and Union Counties, Jersey City serving Hudson County, and Union serving Union County.


Dr. Amanda Gredzik is an optometrist with a strong focus on therapeutic eye care, specializing in dry eye treatment, including the use of amniotic membranes and punctal plugs.
Understanding Conjunctival Papilloma
Conjunctival papilloma refers to a benign epithelial tumor characterized by multiple branching fronds, often accompanied by a central vascular core. These lesions commonly result from an infection with human papillomavirus (HPV), particularly types 6 and 11, known for causing benign warts on the skin and genital condylomas. While the majority of these growths remain non-threatening, their appearance and potential to recur after treatment can be concerning for patients.
Often observed in younger patients as a result of viral infection, conjunctival papilloma can also develop in older adults when associated with factors such as ultraviolet (UV) exposure. The lesion’s characteristic appearance – lobulated with a central feeder vessel – provides valuable clues to our eye doctors during examination. Understanding this condition is essential for accurate diagnosis and to tailor treatment that minimizes discomfort and the risk of recurrence.





HPV Infection and Transmission
The primary contributor to conjunctival papilloma is infection with the human papillomavirus (HPV). Here’s the thing: HPV, especially types 6 and 11, is known to infect superficial epithelial cells, leading to the characteristic growth patterns associated with papillomatous lesions. In some cases, other HPV types such as type 33 or even the higher-risk types 16 and 18 can be involved, though these associations are less common.
Transmission of the virus can occur through direct contact with infected tissues or even by autoinoculation from other parts of the body. For children, there may be a history of maternal HPV transmission during birth, and in adults, self-inoculation by touching the eyes with contaminated hands could be the culprit. Overall, the viral origin underpins the development of these lesions, and repeated exposure or immune factors can influence both the formation and recurrence of the growth.

Clinical Presentation
Conjunctival papillomas typically present as a fleshy, grayish-red mass on the surface of the eye. The lesion most often comes in two clinical forms: the pedunculated type, which appears to be attached by a narrow stalk, and the sessile type, which is flatter and broader. Most patients do not experience pain or significant visual impairment; however, larger growths may disrupt tear flow and cause irritation or a feeling of grittiness in the eye.


Histopathology and Growth Patterns





Risk Factors and Epidemiology

Diagnosis and Examination Process





Follow-Up and Prognosis

Prevention and Risk Reduction Strategies


Treatment Options for
Conjunctival Papilloma
Treatment for conjunctival papilloma is tailored to the patient’s symptoms, lesion size, and location. Let me explain: while small growths that do not cause discomfort may be observed without intervention, larger or symptomatic papillomas often require treatment to alleviate irritation and prevent cosmetic concerns. Our eye doctors typically recommend one or a combination of the following treatments:
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Your Trusted Eye Doctors Serving Central and Northern NJ
The diagnosis and treatment of conjunctival papilloma can greatly enhance your comfort and peace of mind. At Associated Eye Physicians & Surgeons of New Jersey, we emphasize a comprehensive approach tailored to your individual needs. Our eye doctors will guide you through evaluation, treatment, and ongoing care for optimal results. With our focus on patient well-being, you can trust that your eye health is in good hands. Experience personalized, expert eye care by scheduling an appointment with our eye doctors in Belleville, Jersey City, Rahway, or Union, NJ.
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At Associated Eye Physicians of NJ, we’ve built our reputation on care that’s local, personal, and easy to get to. With offices in Belleville, Union, Jersey City, and Rahway, we’re proud to serve a wide range of communities across North and Central Jersey. Our Belleville team welcomes patients from all over Essex County, including Newark, Bloomfield, and Nutley. Rahway welcomes patients from across Middlesex and Union Counties, including nearby patients from Elizabeth, Avenel, Woodbridge, and Perth Amboy. Our Union office is a favorite for families from Union County, especially for those in Elizabeth and Cranford. And in Jersey City, we care for Hudson County residents, including our neighbors in Hoboken and Bayonne.